| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | MKN28, MKN45, AGS | Down | PIK3CB | PI3K-Akt signaling pathway | MicroRNA-125b-2 act as potential tumor suppressors by down-regulating the expression of PIK3CB in gastric cancer. | Riquelme et al., 2016 |
| Breast cancer | MCF-7 | Down | MCL1 | Mitochondria-caspase-3 pathway | Combined effect of miR-125b and doxorubicin causes the loss of mitochondrial membrane potential and mitochondria outer membrane permeability. | Xie et al., 2015 |