Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | Stomach | Down | IGF1R | IRS1 signaling pathway | MicrRNA-1271 regulates cisplatin resistance in human gastric cancer cells through inhibiting the IGF1R/IRS1 pathway. | Yang et al., 2014 |
Gastric cancer | Stomach | Down | IRS1 | IRS1 signaling pathway | Upregulation of miR-1271 suppresses the levels of IRS1, inhibits proliferation of cells, and sensitized cells to DDP-induced apoptosis. | Yang et al., 2014 |
Hepatocellular carcinoma | SMMC-7721, SNU-449, HEK293T | Down | BLVRB | NF-Kappa B signaling pathway | MicroRNA-127 represses NF-Kappa B activity by directly inhibiting biliverdin reductase B (BLVRB) in hepatocellular carcinoma cells. | Huan et al., 2016 |