microRNA Name:

hsa-miR-127

Gene Score: 0.003

Pathway Score: 0.0082

Disease Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
Gastric cancer Stomach Down IGF1R IRS1 signaling pathway MicrRNA-1271 regulates cisplatin resistance in human gastric cancer cells through inhibiting the IGF1R/IRS1 pathway.
Yang et al., 2014
Gastric cancer Stomach Down IRS1 IRS1 signaling pathway Upregulation of miR-1271 suppresses the levels of IRS1, inhibits proliferation of cells, and sensitized cells to DDP-induced apoptosis.
Yang et al., 2014
Hepatocellular carcinoma SMMC-7721, SNU-449, HEK293T Down BLVRB NF-Kappa B signaling pathway MicroRNA-127 represses NF-Kappa B activity by directly inhibiting biliverdin reductase B (BLVRB) in hepatocellular carcinoma cells.
Huan et al., 2016