| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | Gastric cancer tissue | Up | TGFBR2 | TGF-beta signaling pathway | MicroRNA-130 acts as an oncogene and promotes cell proliferation by directly inhibiting the expression of TGF-beta-R2 in gastric cancer. | Duan et al., 2016 |
| Cervical cancer | HeLa, Ca Ski | PTEN | NF-Kappa B signaling pathway | Overexpression of microRNA-130a regulates cervical cancer cell growth by inhibiting phosphatase and tensin homolog expression. | Feng et al., 2016 | |
| Prostate cancer | PC-3 | Down | SLAIN1 | Apoptosis pathway | Ectopic expression of microRNA-130a activates apoptotic signaling pathway in taxane-resistant prostate cancer cells via activation of caspase-8. | Fujita et al., 2015 |