microRNA Name:

hsa-miR-132

Gene Score: 0.0152

Pathway Score: 0.041

Disease Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
Chronic lymphocytic leukemia Peripheral blood Up SIRT1 p53 signaling pathway Up-regulation of hsa-miR-132 down-regulates the expression of SIRT1 and induces TP53-dependent apoptosis in chronic lymphocytic leukemia.
Dal et al., 2015
Alzheimer's disease Cerebral cortex Down PTEN PI3K-Akt signaling pathway MicroRNA-132 regulates cell survival by direct suppression of PTEN, which is the key elements of AKT signaling pathway.
Wong et al., 2013
Alzheimer's disease Cerebral cortex Down FOXO3A FoxO signaling pathway MicroRNA-132 regulates cell survival by direct suppression of FOXO3a, which is the key elements of AKT signaling pathway.
Wong et al., 2013
Hepatocellular carcinoma Hep-G2, SMMC-7721, Huh-7 Down PIK3R3 mTOR pathway Overexpression hsa-miR-132 inhibits PIK3R3 expression. miR-132 suppresses proliferation, invasion and migration of HCC through inactivating AKT/mTOR pathway
Liu et al., 2015
Laryngeal squamous cell carcinoma HEp-2, AMC-HN-8 Up FOXO1 PI3K-Akt signaling pathway MicroRNA-132 functions as an oncogene in laryngeal squamous cell carcinoma by regulating the PI3K-Akt signaling pathway.
Lian et al., 2016