Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Primary CNS lymphoma | Lymph node | Down | Myc pathway | Downregulation of hsa-miR-145 is associated with Myc pathway in primary CNS lymphomas. | Fischer et al., 2011 | |
Lung cancer | A-549 | Down | Wnt signaling pathway | hsa-miR-145 suppresses lung cancer cell metastasis and epithelial mesenchymal transition through inhibiting the Oct4 mediated Wnt signaling pathway. | Ling et al., 2015 |