| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Breast cancer | MCF-7, MDA-MB-231 | Down | WNT1 | Wnt signaling pathway | MicroRNA-148a inhibits the migration and invasion of breast cancer cells by down-regulating WNT-1 and suppressing Wnt signaling pathway. | Jiang et al., 2016 |
| Hepatocellular carcinoma | Hepatocyte | SMAD2 | TGF-beta signaling pathway | Overexpression of miR-148a inhibits the expression of SMAD2 and cancer stem cell-like properties in hepatocellular carcinoma cells throughTGF-beta signaling pathway. | Jiang et al., 2014 | |
| Myocarditis | Myocardial | Up | REL A | NF-Kappa B signaling pathway | hsa-miR-148a reduces cardiac injury by repressing NF-Kappa B signaling pathway during acute viral myocarditis. | Bao et al., 2014 |