| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | AGS, MKN-28, MKN-45 | Down | ZBTB2 | p53 signaling pathway | MicroRNA-149 acts as a tumor suppressor through down-regulating ZBTB2 in human gastric cancer. | Wang et al., 2012 |
| Hepatocellular carcinoma | Hepatocyte | AKT | mTOR pathway | hsa-miR-149 acts as a tumor suppressive microRNA and play a vital role in suppressing hepatocellular carcinoma tumorigenesis by modulating by AKT/mTOR pathway. | Zhang et al., 2014 |