microRNA Name:

hsa-miR-185

Gene Score: 0.0152

Pathway Score: 0.041

Disease Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
Hepatitis C virus infection Hep-G2 SREBP2 SREBP pathway Upregulation of microRNA-185 suppresses the expression of SREBP2 by HCV core protein.
Li et al., 2015
Gastric cancer MGC-803, BGC-823, GES-1 Down TRIM29 Wnt signaling pathway Upregulation of miR-185 suppresses TRIM29 expression and activity of Wnt signaling pathway in gastric cancer.
Qiu et al., 2015
Esophageal squamous cell carcinoma Eca-109 Up RAGE RAGE pathway Upregulation of miR-185 inhibits migration and invasion and reduces the capacity to develop distal pulmonary metastases via the RAGE pathway.
Jing et al., 2015
Hepatocellular carcinoma Hepatocyte Down DNMT1 PI3K-Akt signaling pathway hsa-miR-185 acts as a tumor suppressor microRNA that prevents hepatocellular carcinoma cell growth by downregulating DNMT1, leading to PTEN induction and Akt inhibition.
Qadir et al., 2014
Nasopharyngeal carcinoma CNE-2 Down WNT2B Wnt signaling pathway MicroRNA-185 controls the radioresistance of nasopharyngeal carcinoma through targeting WNT2B expression.
Li et al., 2014