| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Non-small cell lung cancer | Lung | Down | HNUDC | ERK pathway | Over-expression of miR-194 suppresses the expression of Mpl/ERK pathway proteins, and inhibits the mitosis and proliferation of non-small cell lung cancer cells. | Zhou et al., 2016 |
| Hepatocellular carcinoma | Hepatocyte | Down | TRIM23 | NF-Kappa B signaling pathway | hsa-miR-23 directly targeted TRIM23. TNF alpha-NF-Kappa B signaling switches off negative regulation by repressing HNF-1 alpha-mediated expression of hsa-miR-194. | Bao et al., 2015 |
| Oral squamous cell carcinoma | SCC-9, SCC-25, | Down | AGK | PI3K-Akt signaling pathway | MicroRNA-194 acts as a potential tumor suppressor by targeting the PI3K-Akt signaling pathway. | Chi et al., 2015 |