Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Non-small cell lung cancer | Lung | Up | P21 | mTOR pathway | MicroRNA-208a regulates the proliferation and radiosensitivity of human lung cancer cells by direct inhibition of p21. | Tang et al., 2016 |
Hepatocellular carcinoma | Hep-G2, Hep-3B | ARID2 | TGF-beta signaling pathway | Overexpression of hsa-miR-208 downregulates ARID2 expression.TGF-beta-1 activated miR-208 promotes HCC cell progression by targeting ARID2 via TGF-beta signaling pathway. | Yu et al., 2015 |