| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Lung cancer | A-549,NCI-H1650 | Up | CTNNBIP1 | Wnt signaling pathway | MicroRNA-214 plays an important role in cancer stem-like cells self-renewal and stemness by down-regulating the expression of CTNNBIP1 in lung adenocarcinoma. | Qi et al., 2015 |
| Breast cancer | Breast | Up | PTEN | PI3K-Akt signaling pathway | MicroRNA-214 functions as oncogene in breast cancer by inhibiting the PI3K-Akt signaling pathway. | Wang et al., 2016 |