| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | MKN-45, SGC-7901 | Down | ROBO1 | Slit/Robo pathway | Overexpression of miR-218 inhibits Robo1 expression and isuppresses tumor cell invasion and metastasis in gastric cancer. | Tie et al., 2010 |
| Hepatocellular carcinoma | Hepatocyte | Down | HOXA10 | PI3K-Akt signaling pathway | Overexpression of miR-218 reduces cancer cell proliferation in hepatocellular carcinoma through PI3K-Akt signaling pathway with possible association of HoxA10. | Xiao et al., 2014 |
| Renal cell carcinoma | A-498, 786-O | CAV2 | Focal adhesion pathway | MicroRNA-218 suppresses cell migration and invasion in renal cell carcinoma by inhibiting caveolin-2 expression. | Yamasaki et al., 2013 |