| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Hepatocellular carcinoma | Hepatocyte | Up | PI3K-Akt signaling pathway | hsa-miR-222 affects cell proliferation, migration and invasion, and enhance the resistance of hepatocellular carcinoma cells to sorafenib via regulation of the PI3K-Akt signaling pathway. | Liu et al., 2014 | |
| Atherosclerosis | HUVEC | PTEN | PTEN pathway | MiR-221 from human aortic smooth muscle cell-derived exosomes inhibits autophagy in HUVECs by modulating PTEN signaling pathway. | Li et al.,2016 |