Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Breast cancer | Breast | Up | PTEN | PI3K-Akt signaling pathway | MicroRNA-29a promotes adriamycin resistance via PTEN/AKT/GSK3-beta pathway through targeting PTEN in breast cancer cells. | Shen et al., 2016 |
Breast cancer | Breast | Up | GSK 3 BETA | PI3K-Akt signaling pathway | MicroRNA-29a promotes adriamycin resistance via PTEN/AKT/GSK3-beta pathway through targeting GSK3-beta in breast cancer cells. | Shen et al., 2016 |
Prostate cancer | DU145, PC-3 | Down | LAMC1 | Laminin signaling pathway | MicroRNA-29a functions as tumor suppressors and promotes cancer cell migration and invasion through down-regulating laminin signaling pathway. | Nishikawa et al., 2014 |