Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Non-small cell lung cancer | Lung | Down | IGF1R | PI3K-Akt signaling pathway | MicroRNA-30a inhibits non-small cell lung cancer cells progression via PI3K-Akt signaling pathway by down-regulating the expression of IGF1R. | Wen et al., 2015 |
Hepatocellular carcinoma | Hep-G2, SMMC-7721, MHCC97 | Down | MTDH | PI3K-Akt signaling pathway | MicroRNA-30a acts as a tumor suppressor by directly suppressing metadherin (MTDH) in hepatocellular carcinoma. | Li et al., 2016 |