Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Breast cancer | MCF-7, MDA-MB-231, MCF-10A | TRADD | NF-Kappa B signaling pathway | MicroRNA-30c-2 down-regulates NF-Kappa B signaling and cell cycle progression in breast cancer through inhibition of TRADD expression. | Shukla et al., 2015 | |
Prostate cancer | DU145 | Down | BCL9 | Wnt signaling pathway | MicroRNA-30c regulates prostate cancer progression by targeting BCL9, the key activator of the Wnt pathway. | Ling et al., 2016 |