Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Non-small cell lung cancer | Lung | Down | PAC1 | MAPK signaling pathway | Upregulation of miR-34c inhibits cell proliferation, colony formation, migration and invasion by suppressing PAC1/MAPK signaling pathway. | Zhou et al., 2015 |
Nasopharyngeal carcinoma | CNE-1, CNE-2, HNE-1, HONE-1 | Down | MET | c-MET signaling pathway | hsa-miR-34c inhibits tumor growth and metastasis in nasopharyngeal carcinoma by suppressing MET. | Li et al., 2015 |