| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Hepatitis C virus infection | Hepatocyte | Up | JAK1 | IFN signaling pathway | Upregulation of microRNA-373 impairs IFN signaling by down-regulating JAK1 molecules. | Mukherjee et al., 2015 |
| Hepatitis C virus infection | Hepatocyte | Up | IRF9 | IFN signaling pathway | Upregulation of microRNA-373 impairs IFN signaling by down-regulating IRF9 molecules. | Mukherjee et al., 2015 |
| Breast cancer | MCF-7, MDA-MB-231, MDA-MB-435 | Up | TXNIP | HIF1-alpha-TWIST signaling pathway | MicroRNA-373 promotes the epithelial-to-mesenchymal transition and metastasis through the HIF1-alpha-TWIST signaling axis in breast cancer. | Chen et al., 2015 |