Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Hepatocellular carcinoma | Hepatocyte | PTEN | PI3K-Akt signaling pathway | Overexpression of hsa-miR-429 directly targets PTEN expression. hsa-miR-429 promotes HCC cell migration and invasion through PI3K-Akt signaling pathway. | Tang et al., 2015 | |
Cervical cancer | C-33 A, HeLa | Down | IKK BETA | NF-Kappa B signaling pathway | MicroRNA-429 acts as a tumor suppressor in cervical carcinogenesisis through regulating the NF-Kappa B signaling pathway by down-regulating IKK-beta expression. | Fan et al., 2016 |