| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Hepatitis C virus infection | Hep-G2 | Down | IL 6 | IL-6-mediated signaling pathway | MicroRNA-449a regulates IL-6-mediated CCL2 expression and STAT3 phosphorylation by down-regulating IL-6R. | Sarma et al., 2014 |
| Hepatitis C virus infection | Hep-G2 | Down | NOTCH1 | Notch signaling pathway | MicroRNA-449a plays an important role in regulating the expression of YKL40 through down-regulating NOTCH1 which is the components of the NOTCH signaling pathway. | Sarma et al., 2012 |