Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | MKN28, MKN45, AGS | Down | TSC1 | PI3K-Akt signaling pathway | MicroRNA-101-2 act as potential tumor suppressors by down-regulating the expression of TSC1 in gastric cancer. | Riquelme et al., 2016 |
Breast cancer | MCF-7 | Down | MIF | MIF signaling pathway | Upregulation of miR-451a suppresses MIF expression and inhibits cell proliferation, colony formation, and invasion of breast cancer cells. | Liu et al., 2015 |