Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | Gastric cancer tissue | Up | Wnt signaling pathway | MicroRNA-483 acts as an oncogene to increase the development of gastric cancer by regulating gastric cancer stem cell growth, invasion and self renewal through the Wnt signaling pathway. | Wu et al., 2016 | |
Tongue squamous cell carcinoma | CAL-27, SCC-9 | FIS1 | Mitochondrial apoptotic pathway | MicroRNA-483 regulates mitochondrial fission and cisplatin sensitivity by inhibiting FIS1 expression in tongue squamous cell carcinoma. | Fan et al., 2015 |