microRNA Name:

hsa-miR-491

Gene Score: 0.0091

Pathway Score: 0.0246

Disease Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
Hepatitis C virus infection Huh-7 Down AKT PI3K-Akt signaling pathway MicroRNA-491 represses the phosphoinositol-3 (PI3) kinase/PI3K-Akt signaling pathway.
Ishida et al., 2011
Hepatocellular carcinoma Hepatocyte Down GIT 1 NF-Kappa B signaling pathway Overexpression of hsa-miR-491 blocks the activation of GIT-1 mediated ERK which inactivate NF-Kappa B signaling pathway
Yang et al., 2016
Cervical cancer HeLa, SiHa, MS751 Down HTERT PI3K-Akt signaling pathway MicroRNA-491 inhibits cervical cancer cell growth through PI3K-Akt signaling pathway by down-regulating human telomerase reverse transcriptase (hTERT) expression.
Zhou et al., 2016