| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Breast cancer | Breast | Down | IQGAP1 | ERK pathway | MicroRNA-506 functions as a tumor suppressor by directly inhibiting IQGAP1 expression in breast cancer cells. | Sun et al., 2015 |
| Osteosarcoma | hFOB 1.19 | Down | AEG 1 | Wnt signaling pathway | MicroRNA-506 acts as a tumor suppressor by down-regulating AEG-1 expression in osteosarcoma through the regulation of the Wnt signaling pathway. | Yao et al., 2016 |
| Pancreatic carcinoma | PANC-1, BxPC-3, CFPAC-1 | Down | SPHK1 | NF-Kappa B signaling pathway | MicroRNA-506 acts as a tumor suppressor microRNA through NF-Kappa B signaling pathway. | Li et al., 2016 |