microRNA Name:

hsa-miR-99a

Gene Score: 0.0152

Pathway Score: 0.041

Disease Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
Non-small cell lung cancer Lung Down IGF 1R IGF signaling pathway MicroRNA-99a promotes proliferation, colony formation and migration through the IGF-1R pathway in non-small cell lung cancer.
Chen et al., 2015
Non-small cell lung cancer Lung Down AKT AKT1 signaling pathway MicroRNA-99a plays an important role in the tumorigenesis and metastasis of non-small cell lung cancer by inhibiting AKT1 signaling pathway.
Yu et al., 2015
Breast cancer MCF-7, MDA-MB-231 Down MTOR mTOR pathway MicroRNA-99a inhibits the breast cancer malignant cancer stem cell phenotype by suppressing the mTOR signaling pathway.
Yang et al., 2014
Cervical cancer HeLa Down MTOR mTOR pathway Increased expression of miR-99a suppresses cell growth and invasion in cervical cancer by inhibiting mTOR signaling pathway.
Wang et al., 2014
Anaplastic thyroid carcinoma SW1736, ARO, FRO Down MTOR mTOR pathway MicroRNA-99a acts as a tumor suppressor and plays an important role in suppressing the tumorigenesis via targeting the mTOR/p- 4E-BP1/p-S6K1 pathway in anaplastic thyroid carcinoma.
Huang et al., 2015