Disease Name:

Asthma

microRNA Score: 0.0172

Gene Score: 0.0122

Pathway Score: 0.0328

Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member Pathway More Details References
hsa-miR-21 Airway smooth muscle Up PTEN PI3K-Akt signaling pathway MicroRNA-21 enhanced proliferation and migration of human airway smooth muscle (HASM) cell in asthma through activation of phosphoinositide 3 kinase pathway.
Liu et al., 2015
hsa-miR-138 Airway smooth muscle PDK1 PI3K-Akt signaling pathway hsa-miR-138 controls ASMC proliferation through directly suppressing the PI3K-Akt signaling pathway.
Liu et al., 2015
hsa-miR-19a Bronchial epithelial cell Up TGFBR2 TGF-beta signaling pathway hsa-miR-19a increased bronchial epithelial cell proliferation in severe asthma through inhibiting TGF-beta receptor 2 mRNA level.
Haj-salem et al., 2015
hsa-miR-10a Airway smooth muscle Up PIK3CA PI3K-Akt signaling pathway MicroRNA-10a regulates human airway smooth muscle cell proliferation through targeting PI3K-Akt signaling pathway.
Hu et al., 2014