Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
hsa-miR-21 | Airway smooth muscle | Up | PTEN | PI3K-Akt signaling pathway | MicroRNA-21 enhanced proliferation and migration of human airway smooth muscle (HASM) cell in asthma through activation of phosphoinositide 3 kinase pathway. | Liu et al., 2015 |
hsa-miR-138 | Airway smooth muscle | PDK1 | PI3K-Akt signaling pathway | hsa-miR-138 controls ASMC proliferation through directly suppressing the PI3K-Akt signaling pathway. | Liu et al., 2015 | |
hsa-miR-19a | Bronchial epithelial cell | Up | TGFBR2 | TGF-beta signaling pathway | hsa-miR-19a increased bronchial epithelial cell proliferation in severe asthma through inhibiting TGF-beta receptor 2 mRNA level. | Haj-salem et al., 2015 |
hsa-miR-10a | Airway smooth muscle | Up | PIK3CA | PI3K-Akt signaling pathway | MicroRNA-10a regulates human airway smooth muscle cell proliferation through targeting PI3K-Akt signaling pathway. | Hu et al., 2014 |