Pathway Name:

Autophagy pathway

microRNA Score: 0.0216

Gene Score: 0.0152

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member More Details References
Parkinson's disease hsa-miR-4487 SH-SY5Y ULK1 MicroRNA-4487 may negatively or positively regulates ULK1-mediated autophagic pathway via targeting ULK1.
Chen et al., 2015
Parkinson's disease hsa-miR-595 SH-SY5Y ULK1 MicroRNA-595 may negatively or positively regulates ULK1-mediated autophagic pathway via targeting ULK1.
Chen et al., 2015
Non-small cell lung cancer hsa-miR-106a Lung Up ULK1 MicroRNA-106a inhibits autophagy and increases sensitivity of lung cancer cells to Src inhibitors through miR-106a-ULK1 signaling pathway.
Rothschild et al., 2016
Prostate cancer hsa-miR-26b LNCaP, DU145, PC-3 Down ULK2 MicroRNA-26b suppresses autophagy in prostate cancer cells by down-regulating ULK2 expression.
Clotaire et al., 2016
Prostate cancer hsa-miR-205 LNCaP, DU145 Down TP53INP1 MicroRNA-205 inhibits autophagy and increases radiosensitivity of prostate cancer cells by down-regulating TP53INP1 expression.
Wang et al., 2016