Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
---|---|---|---|---|---|---|
Gastric cancer | hsa-miR-135a | Stomach | Up | AP 2 ALPHA | MicroRNA-135a enhances BCL-2 through AP-2-alpha and consequently increases cell resistance to apoptosis. | Pan et al., 2014 |
Colorectal cancer | hsa-miR-375 | HCT 116 | BCL 2 | MicroRNA-375 acts as a key player in regulating the pathways responsible for inhibiting the natural history of colorectal cancer tumor cells, through the Bcl-2 pathway. | Zaharie et al., 2015 |