Pathway Name:

BCL-2 pathway

microRNA Score: 0.0086

Gene Score: 0.0061

Disease Micro RNA Tissue/ Cell line MicroRNA regulation Targeted Member More Details References
Gastric cancer hsa-miR-135a Stomach Up AP 2 ALPHA MicroRNA-135a enhances BCL-2 through AP-2-alpha and consequently increases cell resistance to apoptosis.
Pan et al., 2014
Colorectal cancer hsa-miR-375 HCT 116 BCL 2 MicroRNA-375 acts as a key player in regulating the pathways responsible for inhibiting the natural history of colorectal cancer tumor cells, through the Bcl-2 pathway.
Zaharie et al., 2015