| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| B-cell lymphoma | hsa-miR-124 | Down | NF-Kappa B signaling pathway | Ectopic expression of p53 increases the miR-124 levels and suppresses BCL2. Disruption of NF-Kappa B signaling pathway may be associated with abnormal coexpression of BCL2 and poor prognosis in B-cell lymphoma. | Jeong et al., 2015 | |
| Chronic lymphocytic leukemia | hsa-miR-15a | Peripheral blood | Down | Apoptosis pathway | miR-15a downregulates the expression of BCL2 and promotes apoptosis in chronic lymphocytic leukemia. | Cimmino et al., 2005 |
| Chronic lymphocytic leukemia | hsa-miR-16-1 | Peripheral blood | Down | Apoptosis pathway | miR-16-1 downregulates the expression of BCL2 and promotes apoptosis in chronic lymphocytic leukemia. | Cimmino et al., 2005 |
| Atherosclerosis | hsa-miR-497 | HUVEC | Up | Caspase 3 pathway | MiR-497 plays an important role in the development of atherosclerosis by inducing apoptosis via caspase3 pathway. | Wu et al., 2016 |