Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
---|---|---|---|---|---|---|
Hepatocellular carcinoma | hsa-miR-655 | Hep-G2, Huh-7, MHCC97-H, MHCC97-L | Down | ADAM10 | MiR-655 acts as a tumor suppressor by directly inhibiting ADAM10 and indirectly regulating beta-catenin pathway in the development of progression of hepatocellular carcinoma. | Wu et al., 2016 |
Gastric cancer | hsa-miR-1225 | MKN28, AGS, MKN45, BGC-823, MGC-803, SGC-7901 | Down | IRS1 | MicroRNA-1225 inhibits gastric cancer growth and metastatic potential through targeting IRS1 and beta-catenin signaling pathway. | Zheng et al., 2016 |
Breast cancer | hsa-miR-3646 | Breast | Up | GSK 3 BETA | MicroRNA-3646 promotes docetaxel resistance of breast cancer cells via inhibiting expression of GSK-3-beta and activating GSK-3-beta/beta-catenin signaling pathway. | Zhang et al., 2016 |
Hepatocellular carcinoma | hsa-miR-9 | Hepatocyte | TAZ | Overexpression of hsa-miR-9 downregulates TAZ expression. Mir-9 promotes HCC cell proliferation through Beta-catenin pathway. | Higashi et al., 2015 | |
Colorectal cancer | hsa-miR-29c | SW620, LoVo | Down | GNA13 | miR-29c regulates epithelial-to-mesenchymal transition in colorectal cancer via beta-catenin signaling by downregulating GNA13. | Zhang et al., 2014 |
Colorectal cancer | hsa-miR-29c | SW620, LoVo | Down | PTP4A | miR-29c regulates epithelial-to-mesenchymal transition in colorectal cancer via beta-catenin signaling by downregulating PTP4A. | Zhang et al., 2014 |
Cervical cancer | hsa-miR-135a | HeLa, Ca Ski, SiHa | Up | SIAH1 | MicroRNA-135a promotes cervical cancer cell transformation via regulating miR-135a/SIAH1/beta-catenin signaling pathway. | Leung et al., 2014 |
Papillary thyroid carcinoma | hsa-miR-449 | TPC-1, K1, IHH-4, CGTH-W-3 | Down | RET | Up regulation of miR-449 suppresses the growth of papillary thyroid carcinoma by targeting the beta-catenin pathway. | Li et al., 2016 |