Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Influenza virus A infection | hsa-miR-29 | A-549 | Up | Protein kinase A signaling pathway | MicroRNA miR29 inhibits DNMT activity and regulates expression of COX2 and PGE2. Protein kinase A signaling pathway activation and CREB1 phosphorylation also associated to expression of COX2. | Fang et al., 2012 |
Hepatocellular carcinoma | hsa-miR-185 | Hepatocyte | Down | PI3K-Akt signaling pathway | hsa-miR-185 acts as a tumor suppressor microRNA that prevents hepatocellular carcinoma cell growth by downregulating DNMT1, leading to PTEN induction and Akt inhibition. | Qadir et al., 2014 |