| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | hsa-miR-34 | HGC-27 | Down | MicroRNA-34 suppresses EGFR signaling through downstream PI3K signaling cascades and regulates MMP7 expression in gastric carcinoma. | Liu et al., 2014 | |
| Hepatocellular carcinoma | hsa-miR-302b | Hepatocyte | Down | EGFR | MicroRNA-302b targets EGFR, and the cell cycle progression is arrested at the G0/G1-phase. At the same time, the expression of AKT2 is down-regulated, and CCND1 and CDK2 are reduced by miR-302b. Thus, overexpression of miR-302b inhibits the growth of hepatoma cells may due to targeting the EGFR/AKT2/CCND1 pathway. | Wang et al., 2014 |
| Prostate cancer | hsa-miR-135a-1 | PC-3, DU145 | Down | EGFR | Hsa-miR-135a-1 suppresses cell growth and migration of prostate cancer by down-regulating EGFR expression. | Xu et al., 2016 |