| Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| hsa-miR-744 | Lung | Up | PDCD4 | NF-Kappa B signaling pathway | Down-regulation of miR-744 is associated with suppression of laryngeal squamous cell carcinoma metastasis by inactivating NF-Kappa B signaling pathway. | Li et al., 2016 |
| hsa-miR-744 | Lung | Up | PTEN | mTOR pathway | Down-regulation of miR-744 is associated with suppression of laryngeal squamous cell carcinoma metastasis by inactivating AKT/mTOR signaling pathway. | Li et al., 2016 |
| hsa-miR-101 | Lung | CDK8 | Wnt signaling pathway | MicroRNA-101 acts as a tumour repressor that directly suppresses CDK8 expression in laryngeal squamous cell carcinoma. | Li et al., 2015 | |
| hsa-miR-132 | HEp-2, AMC-HN-8 | Up | FOXO1 | PI3K-Akt signaling pathway | MicroRNA-132 functions as an oncogene in laryngeal squamous cell carcinoma by regulating the PI3K-Akt signaling pathway. | Lian et al., 2016 |
| hsa-miR-144 | HEp-2 | Down | IRS1 | PI3K-Akt signaling pathway | MicroRNA-144 acts as a tumor suppressor in laryngeal squamous cell carcinoma by down-regulating IRS1 expression. | Wu et al., 2016 |
| hsa-miR-365a | HEp-2 | Up | PI3K-Akt signaling pathway | MicroRNA-365a functions as an oncomiR and enhances growth and metastasis in laryngeal squamous cell carcinoma through the PI3K-Akt signaling pathway. | Geng et al., 2016 | |
| hsa-miR-340 | HEp-2 | Down | EZH2 | PI3K-Akt signaling pathway | MicroRNA-340 suppresses laryngeal squamous cell carcinoma progression by down-regulating EZH2 expression through PI3K-Akt signaling pathway. | Yu et al., 2016 |
| hsa-miR-221 | HEp-2 | Up | APAF 1 | Apoptosis pathway | MicroRNA-221 enhances the proliferation of laryngeal cancer cells by down-regulating Apaf-1 expression. | Sun et al., 2015 |
| hsa-miR-19a | HEp-2 | Up | TIMP2 | TIMP-2 pathway | MicroRNA-19a functions as an oncogene in the progression of laryngeal squamous cell carcinoma by targeting TIMP-2 expression. | Wu etal., 2013 |