Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
---|---|---|---|---|---|---|
Non-small cell lung cancer | hsa-miR-208a | Lung | Up | mTOR pathway | MicroRNA-208a regulates the proliferation and radiosensitivity of human lung cancer cells by direct inhibition of p21. | Tang et al., 2016 |
Metastatic lung cancer | hsa-miR-708 | Lung | Down | PI3K-Akt signaling pathway | Upregulation of the miRNA-708 inhibits cell survival and metastasis through its direct target p21, and suppresses the PI3K-Akt signaling pathway and stem cell-like characteristics of lung cancer cells. | Wu et al., 2016 |