| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Hepatocellular carcinoma | hsa-miR-125a | Hep-G2, LM3 | Down | PI3K-Akt signaling pathway | MicroRNA-125a directly targets PI3K. Upregulation of MicroRNA-125a suppresses the invasive ability of hepatocellular carcinoma cells through regulation of the PI3K-Akt signaling pathway. | Tang et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-16 | SK-HEP-1 | PI3K-Akt signaling pathway | Upregulation of microRNA-16 suppresses PI3K expression and Akt phosphorylation. MicroRNA-16 overexpression inhibits the proliferation, invasion and metastasis of hepatocellular carcinoma cells, and these effects are associated with the PI3K-Akt signaling pathway. | Wu et al., 2015 |