| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | More Details | References |
|---|---|---|---|---|---|---|
| Non-alcoholic fatty liver disease | hsa-miR-199a | Hep-G2 | Up | CAV1 | Overexpression of miR199a in hepatocytes is associated with impaired FA beta-oxidation in mitochondria and aberrant lipid deposits through the PPAR signaling pathway. | Li et al., 2014 |
| Breast cancer | hsa-miR-378 | MCF-7, MDA-MB-231 | RUNX1 | Ectopic expression of microRNA-378 down-regulates Runx1 and inhibits migration and invasion in breast cancer. | Browne et al., 2016 | |
| Hepatocellular carcinoma | hsa-miR-9 | Hepatocyte | Up | CDH1 | hsa-miR-9 controls CDH1 expression through directly targeting CDH1 and indirectly through PPARA. hsa-miR -9 is the key regulator of HCC oncogenesis via PPAR signaling pathway. | Drakaki et al., 2015 |
| Hepatocellular carcinoma | hsa-miR-9 | Hepatocyte | Up | PPARA | hsa-miR-9 controls CDH1 expression through directly targeting CDH1 and indirectly through PPARA. hsa-miR -9 is the key regulator of HCC oncogenesis via PPAR signaling pathway. | Drakaki et al., 2015 |