Micro RNA | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
hsa-miR-7 | SH-SY5Y | Up | KEAP1 | Nrf2 signaling pathway | MicroRNA-7 is upregulated in the brain, suppresses the expression of Keap1 in human neuroblastoma cells. Subsequently, this event activates Nrf2 pathway. | Kabaria et al., 2015 |
hsa-miR-137 | HEK293 | Up | NMDAR2 | Neuroactive ligand-receptor interaction pathway | MicroRNA-137 directly regulates Neuroactive ligand-receptor interaction pathway through downregulating NMDAR2. | Kong et al., 2015 |
hsa-miR-137 | HEK293 | Up | D2R | Neuroactive ligand-receptor interaction pathway | MicroRNA-137 directly regulates Neuroactive ligand-receptor interaction pathway through downregulating D2R. | Kong et al., 2015 |
hsa-miR-137 | HEK293 | Up | GABA B R3 | Neuroactive ligand-receptor interaction pathway | MicroRNA-137 directly regulates Neuroactive ligand-receptor interaction pathway through downregulating GABA-B-R3. | Kong et al., 2015 |
hsa-miR-4487 | SH-SY5Y | ULK1 | Autophagy pathway | MicroRNA-4487 may negatively or positively regulates ULK1-mediated autophagic pathway via targeting ULK1. | Chen et al., 2015 | |
hsa-miR-595 | SH-SY5Y | ULK1 | Autophagy pathway | MicroRNA-595 may negatively or positively regulates ULK1-mediated autophagic pathway via targeting ULK1. | Chen et al., 2015 | |
hsa-miR-7 | SH-SY5Y | Up | REL A | Glycolysis pathway | MicroRNA-7 increases Glut3 expression, promotes glycolysis, and subsequently inhibits MPP(+)-induced cell death by targeting RelA. | Chaudhuri et al., 2015 |
hsa-miR-7 | HEK293 | Up | ALPHA SYNUCLEIN | mTOR pathway | MicroRNA-7 protects neurons from cell death by interfering with the MPP+-induced suppression of mTOR signaling pathway. | Fragkouli et al., 2014 |
hsa-miR-153 | HEK293 | Up | ALPHA SYNUCLEIN | mTOR pathway | MicroRNA-153 protects neurons from cell death by interfering with the MPP+-induced suppression of mTOR signaling pathway. | Fragkouli et al., 2014 |
hsa-miR-153 | SH-SY5Y | Up | NRF2 | Nrf2 signaling pathway | MicroRNA-153 directly targets Nrf2-antioxidant network which results an aberrant cellular survival events. | Narasimhan et al., 2014 |