| Disease | Micro RNA | Tissue/ Cell line | MicroRNA regulation | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Multiple myeloma | hsa-miR-451 | Multiple myeloma cell lines | Up | PI3K-Akt signaling pathway | MicroRNA-451 down-regulates TSC1 to mediate PI3K/Akt/mTOR signaling, which plays an important role in myeloma stem cell biology. | Du et al., 2015 |
| Gastric cancer | hsa-miR-451a | MKN28, MKN45, AGS | Down | PI3K-Akt signaling pathway | MicroRNA-101-2 act as potential tumor suppressors by down-regulating the expression of TSC1 in gastric cancer. | Riquelme et al., 2016 |