| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | Gastric cancer tissue | Up | FAS | Caspase 3 pathway | MicroRNA-106a acts as an oncogene through down-regulating FAS in gastric cancer involving in promotion of cell growth and invasion. | Zhu et al., 2016 |
| Gastric cancer | SGC-7901 | Up | PTEN | PI3K-Akt signaling pathway | MicroRNA-106a regulates cisplatin resistance in gastric cancer cells by targeting PI3K-Akt signaling pathway. | Fang et al., 2013 |
| Gastric cancer | Stomach | Up | FAS | Apoptosis pathway | Upregulation of miR-106a functions as an oncogene in gastric carcinogenesis and impair Apoptosis pathway by inhibiting FAS. | Wang et al., 2013 |
| Non-small cell lung cancer | Lung | Up | ULK1 | Autophagy pathway | MicroRNA-106a inhibits autophagy and increases sensitivity of lung cancer cells to Src inhibitors through miR-106a-ULK1 signaling pathway. | Rothschild et al., 2016 |