Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Prostate cancer | LNCaP | Down | FNDC1 | miRNA-1207-3p/FNDC1/FN1/AR regulatory pathway | Over-expression of microRNA-1207 suppresses proliferation, migration, and promotes apoptosis through inhibiting FNDC1 expression. | Das et al., 2016 |
Ovarian cancer | A2780, SK-OV-3, COV362 | Up | SFRP1 | Wnt signaling pathway | MicroRNA-1207 plays an important role in regulating the cancer stem cell-like phenotype through targeting SFRP1 by activating the Wnt signaling pathway in ovarian cancer. | Wu et al., 2015 |
Ovarian cancer | A2780, SK-OV-3, COV362 | Up | AXIN2 | Wnt signaling pathway | MicroRNA-1207 plays an important role in regulating the cancer stem cell-like phenotype through targeting AXIN2 by activating the Wnt signaling pathway in ovarian cancer. | Wu et al., 2015 |
Ovarian cancer | A2780, SK-OV-3, COV362 | Up | ICAT | Wnt signaling pathway | MicroRNA-1207 plays an important role in regulating the cancer stem cell-like phenotype through targeting ICAT by activating the Wnt signaling pathway in ovarian cancer. | Wu et al., 2015 |