| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Anaplastic large cell lymphoma | Karpas-299, SU-DHL-1, SUP-M2 | Up | FOXO1 | Jak-STAT signaling pathway | hsa-miR-135b downregulates FOXO1 in anaplastic large cell lymphoma pathogenesis. miR-135b acts as a downstream mediator of Jak-STAT signaling pathway. | Matsuyama et al., 2011 |
| Anaplastic large cell lymphoma | Karpas-299, SU-DHL-1, SUP-M2 | Up | GATA3 | Jak-STAT signaling pathway | hsa-miR-135b downregulates GATA3, rendering the IL-17 producing immunophenotype to anaplastic large cell lymphoma. miR-135b acts as a downstream mediator of Jak-STAT signaling pathway. | Matsuyama et al., 2011 |
| Anaplastic large cell lymphoma | Karpas-299, SU-DHL-1, SUP-M2 | Up | STAT6 | Jak-STAT signaling pathway | hsa-miR-135b downregulates STAT6, rendering the IL-17 producing immunophenotype to anaplastic large cell lymphoma. miR-135b acts as a downstream mediator of Jak-STAT signaling pathway. | Matsuyama et al., 2011 |
| Breast cancer | Breast | LATS2 | Hippo signaling pathway | MicroRNA-135b directly targets large tumor suppressor kinase 2, a important component of the Hippo pathway. | Hua et al., 2016 |