Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Hepatocellular carcinoma | Hepatocyte | Down | WNT1 | Wnt signaling pathway | hsa-miR-148b suppresses the expression of Wnt-1. Deregulated expression of hsa-miR-148b is associated with poor prognosis and aggressive phenotype of hepatocellular carcinoma through targeting Wnt signaling pathway. | Zhang et al., 2015 |
Hepatocellular carcinoma | Hepatocyte | Down | BETA CATENIN | Wnt signaling pathway | hsa-miR-148b suppresses the expression of beta-catenin. Deregulated expression of hsa-miR-148b is associated with poor prognosis and aggressive phenotype of hepatocellular carcinoma through targeting Wnt signaling pathway. | Zhang et al., 2015 |
Hepatocellular carcinoma | Hepatocyte | Down | MYC | Wnt signaling pathway | hsa-miR-148b suppresses the expression of c-Myc. Deregulated expression of hsa-miR-148b is associated with poor prognosis and aggressive phenotype of hepatocellular carcinoma through targeting Wnt signaling pathway. | Zhang et al., 2015 |