| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Parkinson's disease | HEK293 | Up | ALPHA SYNUCLEIN | mTOR pathway | MicroRNA-153 protects neurons from cell death by interfering with the MPP+-induced suppression of mTOR signaling pathway. | Fragkouli et al., 2014 |
| Parkinson's disease | SH-SY5Y | Up | NRF2 | Nrf2 signaling pathway | MicroRNA-153 directly targets Nrf2-antioxidant network which results an aberrant cellular survival events. | Narasimhan et al., 2014 |
| Hepatocellular carcinoma | Hepatocyte | Up | WWOX | Wnt signaling pathway | Overexpression of hsa-miR-153 downregulates WWOX, a tumor suppressor and inhibitor of Wnt signaling pathway in hepatocellular carcinoma. | Hua et al., 2015 |