Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Hepatocellular carcinoma | Hepatocyte | Up | USP7 | p53 signaling pathway | Overexpression of hsa-miR-205 represses the expression of USP7. Mir-205 modulates p53 signaling pathway and cell proliferation levels in hepatocellular carcinoma cell. | Zhu et al., 2015 |
Prostate cancer | LNCaP, DU145 | Down | TP53INP1 | Autophagy pathway | MicroRNA-205 inhibits autophagy and increases radiosensitivity of prostate cancer cells by down-regulating TP53INP1 expression. | Wang et al., 2016 |