Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Prostate cancer | LNCaP, DU145, BPH-1 | Down | PAK6 | PAK6-LIMK1 signaling pathway | Decreased expression of microRNA-23a inhibits the metastasis by blocking the PAK6-LIMK1 signaling pathway in prostate cancer. | Cai et al., 2015 |
Ovarian cancer | OVCA3, SK-OV-3 | Up | ST7 | MAPK signaling pathway | MicroRNA-23a suppresses proliferation, migration and invasion of epithelial ovarian cancer cells by down-regulating ST7 expression. | Yang et al., 2016 |
Nasopharyngeal carcinoma | CNE-1, CNE-2 | Down | IL 8 | Jak-STAT signaling pathway | Decreased expression of miR-23a enhances nasopharyngeal carcinoma cell radioresistance through activation of Jak-STAT signaling pathway. | Qu et al., 2015 |