| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | - | Up | AKT | PI3K-Akt signaling pathway | The miR-29b controls cisplatin resistance of gastric cancer cell by suppressing PI3K-Akt signaling pathway. | Chen et al., 2015 |
| Hepatocellular carcinoma | LX-1, HSC-T6 | Down | PIK3R1 | PI3K-Akt signaling pathway | hsa-miR-29b directly targets PIK3R1 and AKT3, causing inactivation of PI3K-Akt signaling pathway and inducting apoptosis of hepatic stellate cells (HSCs). | Wang et al., 2015 |
| Hepatocellular carcinoma | LX-1, HSC-T6 | Down | AKT3 | PI3K-Akt signaling pathway | hsa-miR-29b directly targets PIK3R1 and AKT3, causing inactivation of PI3K-Akt signaling pathway and inducting apoptosis of hepatic stellate cells (HSCs). | Wang et al., 2015 |
| Prostate cancer | DU145, PC-3 | Down | LAMC1 | Laminin signaling pathway | MicroRNA-29b functions as tumor suppressors and promotes cancer cell migration and invasion through down-regulating laminin signaling pathway | Nishikawa et al., 2014 |