| Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
|---|---|---|---|---|---|---|
| Gastric cancer | Stomach | Down | SP1 | PI3K-Akt signaling pathway | MicroRNA-335 acts as a metastasis suppressor through down-regulating SP1 directly and indirectly via the Bcl-w-induced phosphoinositide 3-kinase-Akt-Sp1 pathway in gastric cancer. | Xu et al., 2012 |
| Breast cancer | MCF-7 | Down | MET | c-MET signaling pathway | MicroRNA-335 inhibits breast cancer cell migration by down-regulating the HGF/c-Met pathway. | Gao et al., 2015 |