Disease | Tissue/ Cell line | MicroRNA regulation | Targeted Member | Pathway | More Details | References |
---|---|---|---|---|---|---|
Non-small cell lung cancer | Lung | Up | AXIN2 | Wnt signaling pathway | Upregulation of miR-582 down-regulates the expression of AXIN2, the negative regulators of the Wnt signaling pathway. | Fang et al., 2015 |
Non-small cell lung cancer | Lung | Up | DKK3 | Wnt signaling pathway | Overexpressed miR-582 regulates lung cancer stem cell-like traits by activating Wnt-beta-catenin signaling through targeting DKK3. | Fang et al., 2015 |
Non-small cell lung cancer | Lung | Up | SFRP1 | Wnt signaling pathway | Increased expression of miR-582 inhibits the expression of SFRP1, the negative regulators of the Wnt signaling pathway. | Fang et al., 2015 |